发明申请
- 专利标题: HETEROCYCLIC COMPOUND AND H1 RECEPTOR ANTAGONIST
- 专利标题(中): 杂环化合物和H1受体拮抗剂
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申请号: US13699892申请日: 2011-05-23
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公开(公告)号: US20130085127A1公开(公告)日: 2013-04-04
- 发明人: Makoto Okada , Koichi Hasumi , Takahiro Nishimoto , Miwa Yoshida , Kouki Ishitani , Tomoji Aotsuka , Hashime Kanazawa
- 申请人: Makoto Okada , Koichi Hasumi , Takahiro Nishimoto , Miwa Yoshida , Kouki Ishitani , Tomoji Aotsuka , Hashime Kanazawa
- 申请人地址: JP Tokyo
- 专利权人: ASKA Pharmaceutical Co., Ltd
- 当前专利权人: ASKA Pharmaceutical Co., Ltd
- 当前专利权人地址: JP Tokyo
- 优先权: JP2010-122125 20100527; JP2010-165134 20100722
- 国际申请: PCT/JP2011/061734 WO 20110523
- 主分类号: C07D405/06
- IPC分类号: C07D405/06 ; C07D401/06 ; C07D211/46
摘要:
A heterocyclic compound useful as an antiallergic agent is provided.A compound represented by the following formula (1) or a salt thereof: wherein the ring A is a homocyclic or heterocyclic ring; the ring B is a heterocyclic ring which contains G and nitrogen atom N as constituent atoms thereof, wherein G is CH or N; R1 is a carbonyl group or an alkylene group; R2a and R2b are an alkyl group, a cycloalkyl group, an aryl group, or a heterocyclic group; X is an oxygen atom or a sulfur atom; Z is a hydroxyl group, an alkoxy group, a cycloalkyloxy group, an aryloxy group, an aralkyloxy group, an amino group, or an N-substituted amino group; and n is 0 or 1; with the proviso that when the ring A is a benzene ring or when the ring B is a piperazine ring, R1 is an alkylene group which may have a substituent.
公开/授权文献
- US09365553B2 Heterocyclic compound and H1 receptor antagonist 公开/授权日:2016-06-14
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