Methods, systems, and techniques for automatically presenting commercial opportunities in a gesture-based user interface are provided. Example embodiments provide a Gesture Based Content Presentation System (GBCPS), which enables a gesture-based user interface to present an opportunity for commercialization related to a portion of electronic input that has been indicated by a received gesture. In overview, the GBCPS allows a portion (e.g., an area, part, etc.) of electronically presented content to be dynamically indicated by a gesture. The GBCPS then examines the indicated portion in conjunction with a set of (e.g., one or more) factors to determine an opportunity for commercialization to present. An opportunity for commercialization may come in many forms, including, for example, a web page, code, document, or the like. Once the opportunity for commercialization is determined, it is then presented to the user, for example, using a separate panel, an overlay, or in any other fashion.