A code sequence made up multiple instructions and specifying an offset from a base address is identified in an object file. The offset from the base address corresponds to an offset location in a memory configured for storing an address of a variable or data. The identified code sequence is configured to perform a memory reference function or a memory address computation function. It is determined that the offset location is within a specified distance of the base address and that a replacement of the identified code sequence with a replacement code sequence will not alter program semantics. The identified code sequence in the object file is replaced with the replacement code sequence that includes a no-operation (NOP) instruction or having fewer instructions than the identified code sequence. Linked executable code is generated based on the object file and the linked executable code is emitted.