Disclosed are a method and an apparatus for operating multi-band and multi-cell. An Enhanced Node B (eNB) transmits a synchronization channel and a broadcasting channel for narrow-band user equipments (UEs) through a first band narrower than a system band, the first band being located in a center band of the system band, and transmits a control channel for scheduling a data channel for a first narrow-band UE which is one of the narrow-band UEs through a second band equal to or wider than the first band, the second band not overlapping the first band within the system band. The first band is designed to be matched to a band where the synchronization channel and the broadcasting channel of a host cell using an entire system band are transmitted.