发明申请
- 专利标题： FET Sensor and Methods for Detecting Melamine
- 专利标题（中）： FET传感器和检测三聚氰胺的方法
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申请号： US13648396申请日： 2012-10-10
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公开(公告)号： US20130089932A1公开(公告)日： 2013-04-11
- 发明人: Qiang Wu , Wenchuang Hu , Ruhai Tian
- 申请人： Qiang Wu , Wenchuang Hu , Ruhai Tian
- 主分类号： H01L29/78
- IPC分类号： H01L29/78 ; G01N33/53
摘要：
The present invention provides a device and methods for the detection and quantification melamine in a sample by rapid and specific electrochemical detection. The present invention includes using a field-effect transistor (FET) biosensor having an open Si channel with a melamine antigen, or hapten, or an antibody, anchored via a linker molecule such as self assembled monolayer to the surface of the gate dielectric of the said open Si channel. The anchoring molecule having the capability of detecting melamine directly or indirectly by selectively binding melamine antibodies, which changes a field-effect on a Si channel, causing a change in conductivity of the FET. This change in conductivity can be measured and is used to determine the presence or absence of melamine in a sample compared to a standard signal or pre-measured database.
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