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发明申请
US20130090480A1 Benzoxazole Derivatives Having Inhibitory Activity Against Interleukin-6, Preparation Method Thereof, and Pharmaceutical Composition Containing the Same 有权
对白介素-6具有抑制活性的苯并恶唑衍生物及其制备方法以及含有其的药物组合物

  • 专利标题： Benzoxazole Derivatives Having Inhibitory Activity Against Interleukin-6, Preparation Method Thereof, and Pharmaceutical Composition Containing the Same
  • 专利标题（中）： 对白介素-6具有抑制活性的苯并恶唑衍生物及其制备方法以及含有其的药物组合物
  • 申请号： US13805136
    申请日： 2011-06-17
  • 公开(公告)号： US20130090480A1
    公开(公告)日： 2013-04-11
  • 发明人: Hea Young Park Choo , Young Kook Kim , Jung Ho Choi , Jin Ah Kim
  • 申请人： Hea Young Park Choo , Young Kook Kim , Jung Ho Choi , Jin Ah Kim
  • 优先权： KR10-2010-0057844 20100618
  • 国际申请： PCT/KR2011/004436 WO 20110617
  • 主分类号： C07D263/58
  • IPC分类号： C07D263/58
Benzoxazole Derivatives Having Inhibitory Activity Against Interleukin-6, Preparation Method Thereof, and Pharmaceutical Composition Containing the Same
摘要：
The present invention relates to benzoxazole derivatives represented by the Formula 1, which has an inhibitory activity against interleukin-6 (IL-6), a method for preparation thereof, and a pharmaceutical composition containing the same. The compound represented by the Formula 1 according to the present invention has a superior inhibitory activity against interleukin-6, and therefore, can be practically applied for prevention and treatment of diseases caused by abnormal interleukin-6 activity.
摘要（中）：

本发明涉及对白细胞介素-6（IL-6）具有抑制活性的式1所示的苯并恶唑衍生物及其制备方法以及含有该衍生物的药物组合物。 由本发明的式1表示的化合物对白细胞介素-6具有优异的抑制活性，因此可以实际应用于预防和治疗由异常白细胞介素-6活性引起的疾病。

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