Techniques are provided for overcoming uplink (UL) interference at a femtocell or the like by modifying the estimated interference-plus-noise power in UL power control. In one example, the modification can be specified by a method, operable by a network entity, that may involve determining a level of excess received interference based at least in part on out-of-cell interference (Ioc). In another example, the modification can be specified by a method, operable by a network entity, that may involve determining a difference between the downlink transmit powers of the high-speed downlink packet access (HSDPA) serving and non-serving cells, with which the UE are in soft handover (SHO) in uplink and is served by the HSDPA serving cell in downlink.