Invention Application
US20130096056A1 AMINOTHIAZOLE DERIVATIVES AS HUMAN STEAROYL-COA DESATURASE INHIBITORS
审中-公开
作为人类硬脂酸脱乙酰酶抑制剂的氨基噻唑衍生物
- Patent Title: AMINOTHIAZOLE DERIVATIVES AS HUMAN STEAROYL-COA DESATURASE INHIBITORS
- Patent Title (中): 作为人类硬脂酸脱乙酰酶抑制剂的氨基噻唑衍生物
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Application No.: US13620339Application Date: 2012-09-14
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Publication No.: US20130096056A1Publication Date: 2013-04-18
- Inventor: Jianmin Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Zaihui Zhang
- Applicant: Jianmin Fu , Duanjie Hou , Rajender Kamboj , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Vandna Raina , Shaoyi Sun , Serguei Sviridov , Zaihui Zhang
- Applicant Address: CA Burnaby
- Assignee: XENON PHARMACEUTICALS INC.
- Current Assignee: XENON PHARMACEUTICALS INC.
- Current Assignee Address: CA Burnaby
- Main IPC: C07D277/587
- IPC: C07D277/587 ; C07D417/12 ; A61K31/426 ; A61K31/427 ; A61K45/06 ; C07D417/06 ; A61K38/28 ; A61K38/26 ; A61K31/616 ; A61K31/4439 ; A61K31/5377
Abstract:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where V, W, R1, R2, R3 and R4 are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Information query
