Segmental spinous process implant systems and methods of use are provided for coupling to one or more spinal processes of a cervical, thoracic, and/or lumbar spine. Embodiments of the segmental spinous process implant system include a support member coupled to one or more offset connector. The support member extends adjacent to vertebrae of a cervical, thoracic, and/or lumbar spine. The offset connector extends from the support member between adjacent spinous processes of the spine and supports a pair of spinous process connectors that secure the implant to a spinous process of a vertebra of the spine.