- 专利标题: AXMI-115, AXMI-113, AXMI-005, AXMI-163 AND AXMI-184: INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE
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申请号: US13675572申请日: 2012-11-13
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公开(公告)号: US20130104259A1公开(公告)日: 2013-04-25
- 发明人: Kimberly S. Sampson , Daniel J. Tomso , Shruti Agarwal , Brian McNulty , Chris Campbell
- 申请人: ATHENIX CORPORATION
- 申请人地址: US NC Morrisville
- 专利权人: ATHENIX CORPORATION
- 当前专利权人: ATHENIX CORPORATION
- 当前专利权人地址: US NC Morrisville
- 主分类号: C07K14/325
- IPC分类号: C07K14/325 ; A01N37/18 ; C12N15/82 ; C07K16/12
摘要:
Compositions and methods for conferring insecticidal activity to host cells are provided. Compositions comprising a coding sequence for a delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in host cells. Compositions also comprise transformed host cells. In particular, isolated delta-endotoxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:4, 5, 6, 13, or 14, or the nucleotide sequence set forth in SEQ ID NO:1, 2, 3, 11, or 12, as well as variants and fragments thereof.
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