发明申请
- 专利标题: PEPTIDES USEFUL AS CELL-PENETRATING PEPTIDES
- 专利标题(中): 肽可用作细胞穿刺肽
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申请号: US13557706申请日: 2012-07-25
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公开(公告)号: US20130108662A1公开(公告)日: 2013-05-02
- 发明人: Roland Brock , Rainer Fischer , Mariola Fotin-Mleczek , Hansjoerg Hufnagel , Norbert Windhab
- 申请人: Roland Brock , Rainer Fischer , Mariola Fotin-Mleczek , Hansjoerg Hufnagel , Norbert Windhab
- 申请人地址: DE Darmstadt
- 专利权人: Evonik Roehm GmbH
- 当前专利权人: Evonik Roehm GmbH
- 当前专利权人地址: DE Darmstadt
- 优先权: EP05028755.6 20051230
- 主分类号: C07K14/47
- IPC分类号: C07K14/47
摘要:
A peptide having an amino acid sequence containing at least eight consecutive amino acids of the human lactoferrin protein or of the bovine lactoferrin protein. The peptide is suitable as a cell-penetrating peptide. A complex of the peptide and a cargo molecule non-covalently bound to the peptide. The cargo molecule may be a nucleic acid, an amino acid, a peptide, a protein, a carbohydrate, a lipid, or a small molecule. A method of penetrating or transfecting a cell using the complex.
公开/授权文献
- US09403884B2 Peptides useful as cell-penetrating peptides 公开/授权日:2016-08-02
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