发明申请
- 专利标题： PARATHYROID HORMONE ANALOGS AND USES THEREOF
- 专利标题（中）： PARATHYROID HORMONE ANALOGS及其用途
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申请号： US13697249申请日： 2011-05-12
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公开(公告)号： US20130116180A1公开(公告)日： 2013-05-09
- 发明人: Thomas J. Gardella , John T. Potts, JR. , Harald Juppner , Makoto Okazaki
- 申请人： Thomas J. Gardella , John T. Potts, JR. , Harald Juppner , Makoto Okazaki
- 申请人地址： JP Tokyo US MA Boston
- 专利权人： Chugai Seiyaku Kabushiki Kaisha,The General Hospital Corporation
- 当前专利权人： Chugai Seiyaku Kabushiki Kaisha,The General Hospital Corporation
- 当前专利权人地址： JP Tokyo US MA Boston
- 国际申请： PCT/US11/36222 WO 20110512
- 主分类号： A61K38/29
- IPC分类号： A61K38/29 ; C07K14/635
摘要：
Disclosed are two PTH analog ligands, SP-PTH-AAK and Aib-SP-PTH-AAK, that have long-acting activity at the PTH receptor, as demonstrated both in vitro and in vivo. These polypeptides are thus particularly useful in the treatment of diseases, such as hypoparathyroidism, in which long-acting activity is desired. The method of making the analog polypeptides is also disclosed.
公开/授权文献
- US09492508B2 Parathyroid hormone analogs and uses thereof 公开/授权日：2016-11-15
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