A driving method of a pixel circuit, implemented with five transistors and two capacitors, includes steps of: supplying three control signals and a gate signal to the pixel circuit; modulating an operation state of each control signal and keeping the gate signal being disable so as to reset data of the pixel circuit and have an voltage compensation effect on the pixel circuit; and enabling the gate signal so as to operate the pixel circuit in a data writing period, and supplying, in the data writing period, a data voltage to the pixel circuit so as to change a terminal voltage of a driving transistor, which is used to drive the light-emitting device. A pixel circuit is also provided.