发明申请
- 专利标题： Functional, Cross-Linked Nanostructures for Tandem Optical Imaging and Therapy
- 专利标题（中）： 功能，交联纳米结构的串联光学成像和治疗
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申请号： US13697149申请日： 2011-11-17
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公开(公告)号： US20130137976A1公开(公告)日： 2013-05-30
- 发明人: William L. Neumann , Richard B. Dorshow , John N. Freskos , Karen L. Wooley , Nam S. Lee , Lily Nun Lin , Guorong Sun
- 申请人： William L. Neumann , Richard B. Dorshow , John N. Freskos , Karen L. Wooley , Nam S. Lee , Lily Nun Lin , Guorong Sun
- 国际申请： PCT/US2011/036392 WO 20111117
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K39/395 ; A61M5/00 ; A61K38/22 ; A61K31/20 ; A61K38/16 ; A61K31/70
摘要：
The present invention provides optical agents comprising optically functional cross linked supramolecular structures and assemblies useful for tandem optical imaging and therapy. Supramolecular structures and assemblies of the present invention include optically functional shell-cross linked micelles wherein optical functionality is achieved via incorporation of one or more linking groups that include one or more photoactive moieties. The present invention further includes imaging and therapeutic methods using one or more optical agents of the present invention including optically functional shell cross-linked micelles having an associated therapeutic agent.
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