发明申请
US20130143821A1 HYDROPHOBICALLY-MODIFIED HYALURONAN AND METHODS OF MAKING AND USING THEREOF
审中-公开
疏水改性HYALURONONAN及其制备和使用方法
- 专利标题： HYDROPHOBICALLY-MODIFIED HYALURONAN AND METHODS OF MAKING AND USING THEREOF
- 专利标题（中）： 疏水改性HYALURONONAN及其制备和使用方法
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申请号： US13576994申请日： 2011-02-03
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公开(公告)号： US20130143821A1公开(公告)日： 2013-06-06
- 发明人: Jules John Magda , Grant D. mith , Dmitry Bedrov , Jimmy W. Mays
- 申请人： Jules John Magda , Grant D. mith , Dmitry Bedrov , Jimmy W. Mays
- 申请人地址： US TN Knoxville US UT Salt Lake City
- 专利权人： UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION,UNIVERSITY OF UTAH RESEARCH FOUNDATION
- 当前专利权人： UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION,UNIVERSITY OF UTAH RESEARCH FOUNDATION
- 当前专利权人地址： US TN Knoxville US UT Salt Lake City
- 国际申请： PCT/US11/23544 WO 20110203
- 主分类号： A61K38/14
- IPC分类号： A61K38/14
摘要：
Described herein are modified hyaluronans or the pharmaceutically-acceptable salt or ester thereof, wherein the modified hyaluronan comprises at least one hydrophobic polypeptide covalently bonded to hyaluronan. The modified hyaluronans can be used as viscosupplements in a number of medical applications. The modified hyaluronans can also be used in several biological and medical applications. Methods for preparing the modified hyaluronans are also provided herein.