发明申请
- 专利标题: CONJUGATED BLOOD COAGULATION FACTOR VIII
- 专利标题(中): 凝血因子凝血因子VIII
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申请号: US13643287申请日: 2011-04-28
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公开(公告)号: US20130150302A1公开(公告)日: 2013-06-13
- 发明人: William Henry
- 申请人: William Henry
- 申请人地址: MT Valletta
- 专利权人: CANTAB BIOPHARMACEUTICALS PATENTS LIMITED
- 当前专利权人: CANTAB BIOPHARMACEUTICALS PATENTS LIMITED
- 当前专利权人地址: MT Valletta
- 优先权: GB1007357.5 20100430
- 国际申请: PCT/GB2011/000662 WO 20110428
- 主分类号: C07K14/755
- IPC分类号: C07K14/755 ; A61K45/06 ; A61K38/37
摘要:
The present invention provides a biocompatible polymer conjugated to FVIII via one or more cysteine residues, suitably via a linker across a reduced disulphide bond in FVIII, and pharmaceutical compositions comprising such conjugated forms of FVIII.
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