Invention Application
- Patent Title: Bicyclic Aryl and Heteroaryl Sodium Channel Inhibitors
- Patent Title (中): 双环芳基和杂芳基钠通道抑制剂
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Application No.: US13707096Application Date: 2012-12-06
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Publication No.: US20130150339A1Publication Date: 2013-06-13
- Inventor: Christiane BOEZIO , Howard BREGMAN , James R. COATS , Erin F. DIMAURO , Thomas DINEEN , Bingfan DU , Russell GRACEFFA , Charles KREIMAN , Daniel LA , Isaac E. MARX , Nagasree CHAKKA , Hanh Nho NGUYEN , Emily Anne PETERSON , Matthew WEISS , Katrina W. COPELAND , Holly L. DEAK , Alessandro BOEZIO
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Main IPC: C07D498/04
- IPC: C07D498/04 ; C07D471/04 ; C07D401/14 ; C07D417/12 ; C07D417/14
Abstract:
The present invention provides compounds of Formula I, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.
Public/Granted literature
- US09012443B2 Bicyclic aryl and heteroaryl sodium channel inhibitors Public/Granted day:2015-04-21
Information query
