According to one aspect of the present disclosure, a method and technique for domain based partition and resource group management is disclosed. The method includes: responsive to determining that an operation is being attempted on an object, determining a partition identifier associated with the object; determining a domain identifier associated with a user attempting the operation; determining whether the operation can proceed on the partition based on domain isolation rules, the domain isolation rules indicating rules for allowing or disallowing operations to proceed on the partition based on partition identifiers and domain identifiers; and responsive to determining that the operation on the partition can proceed based on the domain isolation rules, permitting the operation.