发明申请
US20130156796A1 Method of Treatment of Tumors That Are Resistant to EGFR Therapies by EGFR Antibody Cytotoxic Agent Conjugate
有权
用EGFR抗体治疗抗EGFR疗法的肿瘤治疗方法细胞毒素偶联物
- 专利标题: Method of Treatment of Tumors That Are Resistant to EGFR Therapies by EGFR Antibody Cytotoxic Agent Conjugate
- 专利标题(中): 用EGFR抗体治疗抗EGFR疗法的肿瘤治疗方法细胞毒素偶联物
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申请号: US13682948申请日: 2012-11-21
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公开(公告)号: US20130156796A1公开(公告)日: 2013-06-20
- 发明人: Julianto SETIADY , Peter U. Park , Thomas Chittenden
- 申请人: Julianto SETIADY , Peter U. Park , Thomas Chittenden
- 专利权人: ImmunoGen, Inc.
- 当前专利权人: ImmunoGen, Inc.
- 主分类号: A61K47/48
- IPC分类号: A61K47/48
摘要:
The present invention relates to the identification that EGFR antibody immunoconjugates are effective in inhibiting the growth of tumor cells that have developed EGFR and/or ALK resistance mechanisms. Methods of administering the EGFR antibody immunoconjugates to patients having resistant tumor cells is also disclosed.
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