发明申请
- 专利标题: PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS
- 专利标题(中): 作为GPR119调节剂的哌啶取代的LACTAMS
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申请号: US13698257申请日: 2011-05-13
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公开(公告)号: US20130158009A1公开(公告)日: 2013-06-20
- 发明人: Thomas Daniel Aicher , Josef Roland Bencsik , Kevin Ronald Condroski , Jay Bradford Fell , John P. Fischer , Ronald Jay Hinklin , Scott Alan Pratt , Ajay Singh , Timothy M. Turner , Steven Armen Boyd
- 申请人: Thomas Daniel Aicher , Josef Roland Bencsik , Kevin Ronald Condroski , Jay Bradford Fell , John P. Fischer , Ronald Jay Hinklin , Scott Alan Pratt , Ajay Singh , Timothy M. Turner , Steven Armen Boyd
- 国际申请: PCT/US2011/036443 WO 20110513
- 主分类号: C07D413/14
- IPC分类号: C07D413/14 ; C07D405/14 ; C07D401/14
摘要:
Compounds of Formula (I): and pharmaceutically acceptable salts thereof in which X1, X2, L, R3, R4, R5, R6, R6a, R7, R9, R9a, and n have the meanings given in the specification, are modulators of GPR119 and are useful in the treatment or prevention of diseases such as such as, but not limited to, type 2 diabetes, diabetic complications, symptoms of diabetes, metabolic syndrome, obesity, dyslipidemia, and related conditions.
公开/授权文献
- US08754226B2 Piperidinyl-substituted lactams as GPR119 modulators 公开/授权日:2014-06-17
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