发明申请
- 专利标题： ALKOXY PYRIMIDINE PDE10 INHIBITORS
- 专利标题（中）： ALKOXY PYRIMIDINE PDE10抑制剂
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申请号： US13820648申请日： 2011-09-26
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公开(公告)号： US20130158056A1公开(公告)日： 2013-06-20
- 发明人: Christopher D. Cox , Izzat T. Raheem , William D. Shipe , Cory R. Theberge
- 申请人： Christopher D. Cox , Izzat T. Raheem , William D. Shipe , Cory R. Theberge
- 国际申请： PCT/US2011/053194 WO 20110926
- 主分类号： C07D513/04
- IPC分类号： C07D513/04 ; C07D495/04 ; C07D417/14 ; C07D471/04 ; C07D401/14
摘要：
The present invention is directed to 2-alkoxy pyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
公开/授权文献
- US08785467B2 Alkoxy pyrimidine PDE10 inhibitors 公开/授权日：2014-07-22
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