发明申请
- 专利标题: METHOD FOR SECRETORY PRODUCTION OF GLYCOPROTEIN HAVING HUMAN-TYPE SUGAR CHAIN USING PLANT CELL
- 专利标题(中): 使用植物细胞分泌生产人类糖链的糖蛋白的方法
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申请号: US13616878申请日: 2012-09-14
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公开(公告)号: US20130164782A1公开(公告)日: 2013-06-27
- 发明人: Kazuhito FUJIYAMA , Tatsuji Seki
- 申请人: Kazuhito FUJIYAMA , Tatsuji Seki
- 申请人地址: US TX San Antonio
- 专利权人: Phyton Holdings, LLC
- 当前专利权人: Phyton Holdings, LLC
- 当前专利权人地址: US TX San Antonio
- 优先权: JP2001-12519 20010119
- 主分类号: C12P21/00
- IPC分类号: C12P21/00 ; C12N9/00
摘要:
A method for the secretory production of a glycoprotein having a human-type sugar chain, comprising a step of introducing a gene of an enzyme capable of performing a transfer reaction of a galactose residue to a non-reducing terminal acetylglucosamine residue, and a gene of heterologous glycoprotein, to obtain a transformed plant cell, a step of culturing the plant cell, and a step of recovering the culture medium of the plant cell.
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