发明申请
- 专利标题： GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF
- 专利标题（中）： 生长激素分泌受体拮抗剂及其用途
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申请号： US13704052申请日： 2011-06-16
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公开(公告)号： US20130172242A1公开(公告)日： 2013-07-04
- 发明人: Cyril Y. Bowers , David H. Coy , Simon J. Hocart , Gloria S. Tannenbaum
- 申请人： Cyril Y. Bowers , David H. Coy , Simon J. Hocart , Gloria S. Tannenbaum
- 申请人地址： CA QC Montreal US LA New Orleans
- 专利权人： MCGILL UNIVERSITY,THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
- 当前专利权人： MCGILL UNIVERSITY,THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
- 当前专利权人地址： CA QC Montreal US LA New Orleans
- 国际申请： PCT/US11/40728 WO 20110616
- 主分类号： C07K7/08
- IPC分类号： C07K7/08 ; C07K14/00 ; C07K5/08 ; C07K7/06
摘要：
The present invention provides novel peptides that can modulate the ghrelin receptor (growth hormone secretagogue receptor, GHS-R1a and sub-types, isoforms and variants thereof). These peptides are useful as antagonists of the ghrelin receptor as well as inverse agonist, partial agonist or a combination of these activities as medicaments for treatment and prevention of a range of medical conditions including, but not limited to, metabolic and/or endocrine disorders, gastrointestinal disorders, cardiovascular disorders, obesity and obesity-associated disorders, diabetes, central nervous system disorders, genetic disorders, and hyperproliferative disorders.
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