- 专利标题: NOVEL OXAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE
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申请号: US13592580申请日: 2012-08-23
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公开(公告)号: US20130172331A1公开(公告)日: 2013-07-04
- 发明人: Rainer Martin LUEOEND , Rainer MACHAUER , Heinrich RUEEGER , Siem Jacob VEENSTRA
- 申请人: Rainer Martin LUEOEND , Rainer MACHAUER , Heinrich RUEEGER , Siem Jacob VEENSTRA
- 专利权人: NOVARTIS AG
- 当前专利权人: NOVARTIS AG
- 主分类号: C07D413/14
- IPC分类号: C07D413/14 ; A61K31/5355 ; A61K45/06
摘要:
The invention relates to novel oxazine derivatives of formula (I), and pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.
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