发明申请
- 专利标题： METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE COMPOUND
- 专利标题（中）： 生产光活性胺化合物的方法
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申请号： US13757395申请日： 2013-02-01
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公开(公告)号： US20130197234A1公开(公告)日： 2013-08-01
- 发明人: Takeshi Ohkuma , Noriyoshi Arai , Noriyuki Utsumi , Kunihiko Murata , Kunihiko Tsutsumi
- 申请人： Kanto Kagaku Kabushiki Kaisha , National University Corporation Hokkaido University
- 申请人地址： JP Hokkaido JP Tokyo
- 专利权人： National University Corporation Hokkaido University,Kanto Kagaku Kabushiki Kaisha
- 当前专利权人： National University Corporation Hokkaido University,Kanto Kagaku Kabushiki Kaisha
- 当前专利权人地址： JP Hokkaido JP Tokyo
- 优先权： JP2012-19742 20120201
- 主分类号： C07C209/70
- IPC分类号： C07C209/70 ; C07D213/36 ; C07C269/06 ; C07C213/02
摘要：
The present invention relates to methods for producing an optically active amine compound via a highly enantioselective hydrogenation reaction of an imine compound, wherein the imine compound is hydrogenated using a ruthenium metal complex having high catalytic activity and represented by Formula (1) RuXYAB (1) such as RuBr2[(S,S)-xylskewphos][(S,S)-dpen].