发明申请
US20130202599A1 NOVEL IMMUNOGLOBULINS INSERTIONS, DELETIONS, AND SUBSTITUTIONS
有权
新的免疫球蛋白插入物,取代物和取代物
- 专利标题: NOVEL IMMUNOGLOBULINS INSERTIONS, DELETIONS, AND SUBSTITUTIONS
- 专利标题(中): 新的免疫球蛋白插入物,取代物和取代物
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申请号: US13846527申请日: 2013-03-18
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公开(公告)号: US20130202599A1公开(公告)日: 2013-08-08
- 发明人: Gregory Lazar , Bassil Dahiyat , Wei Dang , Sher Bahadur Karki , Omid Vafa
- 申请人: Gregory Lazar , Bassil Dahiyat , Wei Dang , Sher Bahadur Karki , Omid Vafa
- 申请人地址: US CA Monrovia
- 专利权人: Xencor, Inc.
- 当前专利权人: Xencor, Inc.
- 当前专利权人地址: US CA Monrovia
- 主分类号: C07K16/28
- IPC分类号: C07K16/28
摘要:
An Fc variant of a parent Fc polypeptide, wherein said Fc variant exhibits altered binding to one or more FcγRs, wherein said Fc variant comprises at least one amino acid insertion in the Fc region of said parent Fc polypeptide.
公开/授权文献
- US08883147B2 Immunoglobulins insertions, deletions, and substitutions 公开/授权日:2014-11-11
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