发明申请
- 专利标题: CHEMICAL COMPOUNDS - 643
- 专利标题(中): 化学化合物 - 643
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申请号: US13564029申请日: 2012-08-01
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公开(公告)号: US20130203714A1公开(公告)日: 2013-08-08
- 发明人: Robert Hugh Bradbury , Gregory Richard Carr , Alfred Arthur Rabow , Srinivasa Rao Korupoju , Harikrishna Tumma
- 申请人: Robert Hugh Bradbury , Gregory Richard Carr , Alfred Arthur Rabow , Srinivasa Rao Korupoju , Harikrishna Tumma
- 申请人地址: SE Sodertalje
- 专利权人: ASTRAZENECA R&D
- 当前专利权人: ASTRAZENECA R&D
- 当前专利权人地址: SE Sodertalje
- 主分类号: A61K31/5025
- IPC分类号: A61K31/5025 ; A61K31/58 ; A61K31/551 ; C07D487/04 ; C07D471/04
摘要:
The invention concerns bicyclic compounds of Formula I wherein R1, R2, L1, L2, J, Y, k, n, p and r are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of androgen-receptor associated conditions, particularly prostate cancer.
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