- 专利标题： Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy
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申请号： US13792105申请日： 2013-03-10
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公开(公告)号： US20130203749A1公开(公告)日： 2013-08-08
- 发明人: Wilhelm Amberg , Michael Ochse , Udo Lange , Wilfried Braje , Berthold Behl , Wilfried Hornberger , Mario Mezler , Charles Hutchins
- 申请人： Wilhelm Amberg , Michael Ochse , Udo Lange , Wilfried Braje , Berthold Behl , Wilfried Hornberger , Mario Mezler , Charles Hutchins
- 申请人地址： US IL North Chicago DE Wiesbaden
- 专利权人： ABBVIE INC.,ABBVIE DEUTSCHLAND GMBH & CO. KG
- 当前专利权人： ABBVIE INC.,ABBVIE DEUTSCHLAND GMBH & CO. KG
- 当前专利权人地址： US IL North Chicago DE Wiesbaden
- 主分类号： C07D217/18
- IPC分类号： C07D217/18 ; C07D409/12 ; C07D401/04 ; C07D401/08 ; C07D513/04 ; C07D498/04 ; C07D401/12 ; C07D413/14
摘要：
The present invention relates to tetrahydroisoquinoline of the formula (I) or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such tetrahydroisoquinolines, and the use of such tetrahydroisoquinolines for therapeutic purposes. The tetrahydroisoquinolines are GlyT1 inhibitors.
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