发明申请
US20130209457A1 Optimized Fc Variants 有权
优化的Fc变体

Optimized Fc Variants
摘要:
The present invention relates to a variant Fc region comprising an amino acid substitution at position 238 of the Fc region as compared to a human parent Fc region, wherein the variant Fc region comprises a 238D substitution, wherein the variant Fc region binds FcγRIIb with increased binding affinity compared to a human parent Fc region.
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