Invention Application
US20130210851A1 Crystalline forms of a hexahydrofuro[3,4-c]quinoline derivative
审中-公开
六氢呋喃并[3,4-c]喹啉衍生物的结晶形式
- Patent Title: Crystalline forms of a hexahydrofuro[3,4-c]quinoline derivative
- Patent Title (中): 六氢呋喃并[3,4-c]喹啉衍生物的结晶形式
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Application No.: US13587982Application Date: 2012-08-17
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Publication No.: US20130210851A1Publication Date: 2013-08-15
- Inventor: Markus OSTERMEIER , Kai GERLACH , Peter SIEGER
- Applicant: Markus OSTERMEIER , Kai GERLACH , Peter SIEGER
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Priority: EP11178029.2 20110818
- Main IPC: C07D491/20
- IPC: C07D491/20 ; A61K45/06 ; A61K31/4741
![Crystalline forms of a hexahydrofuro[3,4-c]quinoline derivative](/abs-image/US/2013/08/15/US20130210851A1/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to crystalline forms of (3R,9S)-4-isopropyl-7,7-dimethyl-3-(4-(trifluoromethyl)phenyl)-2′,3′,5′,6,6′,7,8,9-octahydro-3H-spiro[furo[3,4-c]quinoline-1,4′-pyran]-9-ol and its hydrochloride or hydrobromide salts, to a process for the manufacture thereof, and to the use thereof in pharmaceutical compositions.
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