A pipe hanger clamp, formed by bending a flat section of metal bar or plate, has two vertical side members which have been cut so their side view is a “C” shape. The lower arms of these two side members are joined by a horizontally extended end wall, about which the side members are bent. Holes in the end wall receive a mounting set screw into a captured nut and another nut to hold a pipe hanger rod for supporting a pipe. An overhead support is clamped between the set screw and the upper arms of the C-shaped side members, such that the load applied to the rod is generally edgewise to the plate thickness, and does not provide an unbending force on the clamp.