Disclosed is a method for establishing a CoMP cooperating set in coordinated multi-point communication, the method comprising the steps of: triggering and starting a coordinated multi-point communication process; according to channel state information of all cells in a measurement cell set measured by a UE, determining a candidate CoMP cooperating set; sending a CoMP cooperating set establishment request to eNodeBs of the cooperating cells in the determined candidate CoMP cooperating set; the eNodeBs being of the cooperating cell and receiving the CoMP cooperating set establishment request responding to the CoMP cooperating set establishment request to the eNodeB of the serving cell of the UE, and sending a CoMP cooperating set establishment response to the eNodeB of the serving cell of the UE; the eNodeB of the serving cell of the UE determining a CoMP cooperating set of the UE according to information of the CoMP cooperating set establishment response; and according to a coordinated multi-point communication mode, sharing data information and service bearer information of the UE of the CoMP cooperating set. The present invention guarantees coordinated multi-point joint transmission/reception, decreases the overhead and complexity of the communication system and furthermore reduces the time delay in the information exchange.