发明申请
- 专利标题： Combination Therapy with an Antitumor Alkaloid
- 专利标题（中）： 联合治疗与抗肿瘤生物碱
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申请号： US13884874申请日： 2011-11-11
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公开(公告)号： US20130266666A1公开(公告)日： 2013-10-10
- 发明人: Victoria Moneo Ocaña , Gema Santamaría Núñez , Luis Francisco García Fernández , Carlos Maria Galmarini , María José Guillén Navarro , Pablo Manuel Avilés Marín
- 申请人： Victoria Moneo Ocaña , Gema Santamaría Núñez , Luis Francisco García Fernández , Carlos Maria Galmarini , María José Guillén Navarro , Pablo Manuel Avilés Marín
- 申请人地址： ES Madrid
- 专利权人： PHARMA MAR, S.A.
- 当前专利权人： PHARMA MAR, S.A.
- 当前专利权人地址： ES Madrid
- 优先权： EP10382300.1 20101112
- 国际申请： PCT/EP11/69976 WO 20111111
- 主分类号： A61K31/4995
- IPC分类号： A61K31/4995 ; A61K31/55 ; A61K31/704 ; A61K31/4164 ; A61K31/513 ; A61K31/7068 ; A61K31/4188 ; A61K31/4375 ; A61K31/337 ; A61K33/24
摘要：
The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhibitors, histone deacetylase inhibitors, nitrogen mustard alkylating agents, nitrosourea alkylating agents, nonclassical alkylating agents, estrogen antagonists, androgen antagonists, mTOR inhibitors, tyrosine kinase inhibitors, and other agents selected from aplidine, ET-743, PM02734 and PM00104, and the use of these combinations in the treatment of cancer.
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