发明申请
US20130267565A1 4- (METHYLAMINOPHENOXY) PYRDIN -3- YL - BENZAMIDE DERIVATIVES FOR TREATING CANCER
有权
用于治疗癌症的4-（甲基氨基苯氧基）哌嗪-3-基 - 苯甲酰胺衍生物
- 专利标题： 4- (METHYLAMINOPHENOXY) PYRDIN -3- YL - BENZAMIDE DERIVATIVES FOR TREATING CANCER
- 专利标题（中）： 用于治疗癌症的4-（甲基氨基苯氧基）哌嗪-3-基 - 苯甲酰胺衍生物
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申请号： US13877276申请日： 2011-10-03
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公开(公告)号： US20130267565A1公开(公告)日： 2013-10-10
- 发明人: Takashi Nakagawa , Makoto Sakamoto , Kazuya Yamaguchi , Yuki Terauchi , Masamichi Shirakura , Yasuo Harada , Yutaka Kojima , Takumi Sumida
- 申请人： Takashi Nakagawa , Makoto Sakamoto , Kazuya Yamaguchi , Yuki Terauchi , Masamichi Shirakura , Yasuo Harada , Yutaka Kojima , Takumi Sumida
- 国际申请： PCT/JP2011/073165 WO 20111003
- 主分类号： C07D213/76
- IPC分类号： C07D213/76
摘要：
The present invention provides a novel compound having an excellent antitumor effect, stability and metabolic stability. The compound of the present invention is represented by the following general formula (1) wherein R1 represents a halogen atom, an aryl group, an aryloxy group or a lower alkyl group optionally substituted with one or more halogen atoms; R2 represents hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group; and; m represents an integer of 1 to 3; provided that when m represents 2 or 3, R1s are the same or different.