发明申请
US20130273007A1 Methods for attenuating virus strains for diagnostic and therapeutic uses
审中-公开
用于减轻病毒株用于诊断和治疗用途的方法
- 专利标题： Methods for attenuating virus strains for diagnostic and therapeutic uses
- 专利标题（中）： 用于减轻病毒株用于诊断和治疗用途的方法
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申请号： US13986866申请日： 2013-06-12
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公开(公告)号： US20130273007A1公开(公告)日： 2013-10-17
- 发明人: Aladar A. Szalay , Yong A. Yu , Nanhai Chen , Qian Zhang
- 申请人： Aladar A. Szalay , Yong A. Yu , Nanhai Chen , Qian Zhang
- 主分类号： A61K35/76
- IPC分类号： A61K35/76
摘要：
Lister strain vaccinia viruses that are encode a modified A34R gene resulting in increased extracellular enveloped virus (EEV) form of the virus and/or increased resistance of the virus to neutralizing antibodies. The viruses can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents.
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