发明申请
- 专利标题: Optimized Fc Variants
- 专利标题(中): 优化的Fc变体
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申请号: US13915608申请日: 2013-06-11
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公开(公告)号: US20130273043A1公开(公告)日: 2013-10-17
- 发明人: Gregory Alan Lazar , Wei Dang , John Desjarlais , Sher Bahadur Karki , Omid Vafa , Robert Hayes , Jost Vielmetter
- 申请人: Gregory Alan Lazar , Wei Dang , John Desjarlais , Sher Bahadur Karki , Omid Vafa , Robert Hayes , Jost Vielmetter
- 申请人地址: US CA Monrovia
- 专利权人: Xencor, Inc.
- 当前专利权人: Xencor, Inc.
- 当前专利权人地址: US CA Monrovia
- 主分类号: C07K16/32
- IPC分类号: C07K16/32 ; C07K16/28
摘要:
The present invention relates to Fc variants having decreased affinity for FcγRIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.
公开/授权文献
- US08753628B2 Optimized Fc variants 公开/授权日:2014-06-17
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