发明申请
- 专利标题： PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS
- 专利标题（中）： 制备MACROLACTAMS的过程和中间件
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申请号： US13993541申请日： 2011-12-13
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公开(公告)号： US20130274463A1公开(公告)日： 2013-10-17
- 发明人: Cheng Chen , Jongrock Kong , Guy Humphrey , Sarah Dolman , Hongmei Li , Matthew T. Tudge , Kelvin Yong , Bangping Xiang , Michael Zacuto
- 申请人： Cheng Chen , Jongrock Kong , Guy Humphrey , Sarah Dolman , Hongmei Li , Matthew T. Tudge , Kelvin Yong , Bangping Xiang , Michael Zacuto
- 国际申请： PCT/US11/64521 WO 20111213
- 主分类号： C07D498/16
- IPC分类号： C07D498/16 ; C07D209/44 ; C07C271/56 ; C07C309/85 ; C07C311/47 ; C07D403/12 ; C07C309/80
摘要：
The present invention relates to macrolactam compounds, intermediates useful in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing and modifying macrolactams. One use of the compounds and methods described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. An example of an HCV inhibitory compound that can be synthesized using the procedures described herein is Compound A and derivative thereof.
公开/授权文献
- US09120818B2 Process and intermediates for preparing macrolactams 公开/授权日：2015-09-01
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