发明申请
- 专利标题: CELL SYSTEMS AND METHODS FOR IMPROVING FATTY ACID SYNTHESIS BY EXPRESSION OF DEHYDROGENASES
- 专利标题(中): 通过表达脱氢酶改善脂肪酸合成的细胞系统和方法
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申请号: US13453235申请日: 2012-04-23
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公开(公告)号: US20130280793A1公开(公告)日: 2013-10-24
- 发明人: Robert Christopher Brown , Jennifer Coppersmith , Prachee Prakash , Srividya Akella , Rekha Seshadri
- 申请人: Robert Christopher Brown , Jennifer Coppersmith , Prachee Prakash , Srividya Akella , Rekha Seshadri
- 申请人地址: US NJ Annandale
- 专利权人: ExxonMobil Research and Engineering Company
- 当前专利权人: ExxonMobil Research and Engineering Company
- 当前专利权人地址: US NJ Annandale
- 主分类号: C12N1/13
- IPC分类号: C12N1/13 ; C12N15/53
摘要:
The invention relates to methods for producing lipids such as fatty acid products in recombinant host cells engineered to express a non-native gene encoding a dehydrogenase. The recombinant microorganisms are able to proliferate at a higher rate as compared with microorganisms that do not express a non-native dehydrogenase gene, and cultures of microorganisms that are engineered for lipid production and that express a non-native dehydrogenase produce more lipid than cultures of control microorganisms that do not include a non-native dehydrogenase gene.
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