发明申请
US20130281304A1 Comprehensive Methylome Map of Myeloid and Lymphoid Commitment from Hematopoietic Proenitors
审中-公开
来自造血干细胞的骨髓和淋巴细胞承诺的综合甲基化图
- 专利标题： Comprehensive Methylome Map of Myeloid and Lymphoid Commitment from Hematopoietic Proenitors
- 专利标题（中）： 来自造血干细胞的骨髓和淋巴细胞承诺的综合甲基化图
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申请号： US13814460申请日： 2011-08-12
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公开(公告)号： US20130281304A1公开(公告)日： 2013-10-24
- 发明人: Andrew P. Feinberg , Irving L. Weissman
- 申请人： Andrew P. Feinberg , Irving L. Weissman
- 优先权： US61373730 20100813
- 国际申请： PCT/US11/47681 WO 20110812
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
Provided herein are differentially methylated regions (DMRs) of multipotent progenitor cells (MPPs) and oligopotent progenitor cells and methods of use thereof. The invention provides methods for detecting and analyzing alterations in the methylation status of DMRs in such progenitor cells as well as methods for differentiating such cells.
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