Embodiments of the present disclosure describe techniques and configurations for handling interference measurements in a wireless communication network. An apparatus may include computer-readable media having instructions and processors coupled with the computer-readable media and configured to execute the instructions to identify, for a serving eNB, a neighboring eNB for which signal interference measurements are to be performed by one or more wireless devices served by the serving eNB, and request that the neighboring eNB transmit typical interference signals within data units which are configured for, and may or may not have, a scheduled physical downlink shared channel transmission. The wireless devices may be configured to perform the signal interference measurements based at least in part on the typical interference signals, which may include non-zero-power signals or zero-power signals. Other embodiments may be described and claimed.