A routing circuit and a circuit having the routing circuit are provided. The circuit includes a plurality of integrated circuits (ICs), a plurality of signal terminals and the routing circuit. Each of the ICs has a plurality of signal channels. The routing circuit is coupled between the ICs and the signal terminals to route the signal channels to the signal terminals. The routing circuit has a plurality of sequencers and a processing circuit. Each of the sequencers is configured to reconfigure an arrangement sequence of the signal channels of a corresponding one of the ICs. The processing circuit is coupled to the sequencers and has a first distributor. The first distributor routes the signal channels to the signal terminals in a group manner based on the arrangement sequences of the signal channels reconfigured by the sequencers according to a control signal.