The present invention provides a method and device for allocating uplink shared channel resource, and a communication system, for solving the problem of the overall performance of the communication system being reduced in an existing allocating method. The method comprises: acquiring the volume of data-to-be-transmitted and an uplink channel quality indication; on the basis of the volume of data-to-be-transmitted acquired, determining at least one set of resource profile of the uplink channel quality indication and a resource number; judging of whether or not the uplink channel quality indication comprised within the at least one set of resource profile is identical to the uplink channel quality indication acquired, if identical, using a corresponding set of resource profile as a final resource profile; and if different, combining an uplink transmission power with the corresponding set of resource profile to determine the final resource profile. Under the premise of ensuring QoS, the present invention allows for minimization of transmission power of each terminal, thus reducing inter-system interference, allowing system performance to be further improved.