Invention Application
- Patent Title: FILOVIRUS FUSION PROTEINS AND THEIR USES
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Application No.: US13882041Application Date: 2011-10-28
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Publication No.: US20130323243A1Publication Date: 2013-12-05
- Inventor: Gerardo Kaplan , Krishnamurthy Konduru , Jerome Jacques , Sina Bavari , Steven Bradfute
- Applicant: Gerardo Kaplan , Krishnamurthy Konduru , Jerome Jacques , Sina Bavari , Steven Bradfute
- Applicant Address: US MD FORT DETRICK US MD Rockville
- Assignee: US ARMY MEDICAL RESEARCH AND MATERIEL COMMAND,The Government of the United States of America as Represented by the Secretary of The Dept of HHS
- Current Assignee: US ARMY MEDICAL RESEARCH AND MATERIEL COMMAND,The Government of the United States of America as Represented by the Secretary of The Dept of HHS
- Current Assignee Address: US MD FORT DETRICK US MD Rockville
- International Application: PCT/US11/58418 WO 20111028
- Main IPC: A61K39/12
- IPC: A61K39/12
Abstract:
This invention provides fusion proteins comprising a Filovirus glycoprotein segment and an immunoglobulin polypeptide segment. The fusion proteins are useful in immunogenic compositions to protect against infections by Filoviruses, such as Ebola virus, in both humans and non-human animals. The fusion proteins are also useful in diagnostic assays to detect Filovirus infections.
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