Invention Application
US20130323271A1 NITRIC OXIDE DONOR NEPRILYSIN INHIBITORS 有权
NITRIC氧化尼龙抑制剂

NITRIC OXIDE DONOR NEPRILYSIN INHIBITORS
Abstract:
In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, R7, R8, Z, X, b, and c are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are nitric oxide donors and have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
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