发明申请
US20130323331A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING INFLAMATORY DISEASE OR ASTHMA CONTAINING AN EXTRACT OF DECASPERMUM FRUTICOSUM
有权
用于预防和治疗炎症性疾病或含有降解物的提取物的ASTHMA的药物组合物
- 专利标题： PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING INFLAMATORY DISEASE OR ASTHMA CONTAINING AN EXTRACT OF DECASPERMUM FRUTICOSUM
- 专利标题（中）： 用于预防和治疗炎症性疾病或含有降解物的提取物的ASTHMA的药物组合物
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申请号： US13985533申请日： 2012-02-07
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公开(公告)号： US20130323331A1公开(公告)日： 2013-12-05
- 发明人: Sei Ryang Oh , Kyung Seop Ahn , Ok-Kyoung Kwon , Hyeong Kyu Lee , Joongku Lee , Hyouk Joung , Mee-Young Lee , Hwa-Young Son , Kyoung-youl Lee , Sang Woo Lee , Hang Jin , Wan Yi Li
- 申请人： Sei Ryang Oh , Kyung Seop Ahn , Ok-Kyoung Kwon , Hyeong Kyu Lee , Joongku Lee , Hyouk Joung , Mee-Young Lee , Hwa-Young Son , Kyoung-youl Lee , Sang Woo Lee , Hang Jin , Wan Yi Li
- 申请人地址： KR Daejeon
- 专利权人： KOREA INSTITUTE OF ORIENTAL MEDICINE
- 当前专利权人： KOREA INSTITUTE OF ORIENTAL MEDICINE
- 当前专利权人地址： KR Daejeon
- 优先权： KR10-2011-0013640 20110216
- 国际申请： PCT/KR2012/000890 WO 20120207
- 主分类号： A61K36/61
- IPC分类号： A61K36/61
摘要：
The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma comprising the extract of Decaspermum fruticosum as an active ingredient. The extract of Decaspermum fruticosum of the present invention inhibited the increase of eosinophils in bronchoalveolar lavage fluid of the ovalbumin-induced asthma animal model, had the activity of inhibiting the secretions of immunoglobulin and chemokine (Eotaxin) in bronchoalveolar lavage fluid and blood, and inhibited the secretions of NO and TNF-α in macrophages. Therefore, the extract of Decaspermum fruticosum of the present invention can be effectively used as an active ingredient of a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma, and of a health functional food for the prevention and improvement of inflammatory disease or asthma.
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