发明申请
US20130338064A1 INSULIN-LIPID COMPLEX,PREPARATION METHOD THEREFOR, AND PREPARATION THEREOF
审中-公开
胰岛素复合物，其制备方法及其制备方法
- 专利标题： INSULIN-LIPID COMPLEX,PREPARATION METHOD THEREFOR, AND PREPARATION THEREOF
- 专利标题（中）： 胰岛素复合物，其制备方法及其制备方法
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申请号： US13810098申请日： 2011-07-14
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公开(公告)号： US20130338064A1公开(公告)日： 2013-12-19
- 发明人: Yuling Liu , Cuiping Zhou , Zhihui Song , Lin Li , Hongliang Wang , Xuejun Xia , Renyun Wang , Wujun Dong , Dujia Jin
- 申请人： Yuling Liu , Cuiping Zhou , Zhihui Song , Lin Li , Hongliang Wang , Xuejun Xia , Renyun Wang , Wujun Dong , Dujia Jin
- 申请人地址： CN Beijing
- 专利权人： Institute of Materia Medica, Chinese Academy of Medical Sciences
- 当前专利权人： Institute of Materia Medica, Chinese Academy of Medical Sciences
- 当前专利权人地址： CN Beijing
- 优先权： CNCN201010226102.7 20100714
- 国际申请： PCT/CN2011/077152 WO 20110714
- 主分类号： C07K17/02
- IPC分类号： C07K17/02
摘要：
Provided are an insulin-lipid complex, a preparation method thereof, and a formulation thereof. The insulin-lipid complex is prepared by compounding insulin and a lipid material in an organic solvent system containing a low boiling point acid, and drying. The mass ratio of insulin to the lipid material is 1:3˜1:20. An oil solution of the insulin-lipid complex and vesicles containing insulin are further provided.
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