发明申请
US20130345222A1 IDENTIFICATION OF HUMAN T2R RECEPTORS THAT RESPOND TO BITTER COMPOUNDS THAT ELICIT THE BITTER TASTE IN COMPOSITIONS, AND THE USE THEREOF IN ASSAYS TO IDENTIFY COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITIONS AND USE THEREOF 审中-公开
识别符合组合物中双歧杆菌组合物的双特异度化合物的人类T2R受体,以及其在测定中的用途,以鉴定组合物中的禁止(块状)双歧杆菌组合物及其用途的化合物

  • 专利标题: IDENTIFICATION OF HUMAN T2R RECEPTORS THAT RESPOND TO BITTER COMPOUNDS THAT ELICIT THE BITTER TASTE IN COMPOSITIONS, AND THE USE THEREOF IN ASSAYS TO IDENTIFY COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITIONS AND USE THEREOF
  • 专利标题(中): 识别符合组合物中双歧杆菌组合物的双特异度化合物的人类T2R受体,以及其在测定中的用途,以鉴定组合物中的禁止(块状)双歧杆菌组合物及其用途的化合物
  • 申请号: US13896913
    申请日: 2013-05-17
  • 公开(公告)号: US20130345222A1
    公开(公告)日: 2013-12-26
  • 发明人: Donald S. KaranewskyJoseph R. FotsingCatherine TachdjianMelissa Arellano
  • 申请人: Donald S. KaranewskyJoseph R. FotsingCatherine TachdjianMelissa Arellano
  • 主分类号: A23L1/22
  • IPC分类号: A23L1/22 A23F5/46
IDENTIFICATION OF HUMAN T2R RECEPTORS THAT RESPOND TO BITTER COMPOUNDS THAT ELICIT THE BITTER TASTE IN COMPOSITIONS, AND THE USE THEREOF IN ASSAYS TO IDENTIFY COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITIONS AND USE THEREOF
摘要:
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions containing that function as bitter taste blockers and the use thereof as bitter taste blockers or flavor modulators in, e.g., coffee and coffee flavored foods, beverages and medicaments. Also, the present invention relates to the discovery of a compound that antagonizes numerous different human T2Rs and the use thereof in assays and as a bitter taste blocker in compositions for ingestion by humans and animals.
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