发明申请
US20130345254A1 CYCLOHEXANE SUBSTITUTED AMINO CYCLOPENTANE DERIVATIVES AS USEFUL CCR2 ANTAGONISTS
审中-公开
CYCLOHEXANE取代的氨基环戊烷衍生物作为有用的CCR2拮抗剂
- 专利标题： CYCLOHEXANE SUBSTITUTED AMINO CYCLOPENTANE DERIVATIVES AS USEFUL CCR2 ANTAGONISTS
- 专利标题（中）： CYCLOHEXANE取代的氨基环戊烷衍生物作为有用的CCR2拮抗剂
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申请号： US14004485申请日： 2012-03-14
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公开(公告)号： US20130345254A1公开(公告)日： 2013-12-26
- 发明人: Anilkumar G. Nair , Joseph A. Kozlowski
- 申请人： Anilkumar G. Nair , Joseph A. Kozlowski
- 国际申请： PCT/US12/28971 WO 20120314
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07C237/24
摘要：
Disclosed are the CCR2 antagonists of Formula I: I or pharmaceutically acceptable salts thereof, wherein A, B, R, and R6 are as defined herein. Also disclosed are pharmaceutical compositions containing the compounds, methods of treatment using the compounds, and compositions to treat diseases or disorders associated with CCR2 activity.