发明申请
US20140005214A1 PIPERIDINONE CARBOXAMIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS
审中-公开
哌啶酮羧酰胺螺旋糖苷CGRP受体拮抗剂
- 专利标题： PIPERIDINONE CARBOXAMIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS
- 专利标题（中）： 哌啶酮羧酰胺螺旋糖苷CGRP受体拮抗剂
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申请号： US14005595申请日： 2012-03-14
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公开(公告)号： US20140005214A1公开(公告)日： 2014-01-02
- 发明人: Ian M. Bell , Mark E. Fraley , Steven N. Gallicchio , Helen J. Mitchell , Cheng Wang
- 申请人： Ian M. Bell , Mark E. Fraley , Steven N. Gallicchio , Helen J. Mitchell , Cheng Wang
- 国际申请： PCT/US12/28976 WO 20120314
- 主分类号： C07D401/12
- IPC分类号： C07D401/12
摘要：
The present invention is directed to piperidinone carboxamide spirohydantoin derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
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