发明申请
- 专利标题: THERAPEUTIC PYRAZOLYL THIENOPYRIDINES
- 专利标题(中): 治疗性吡唑并噻唑啉酮
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申请号: US13864457申请日: 2013-04-17
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公开(公告)号: US20140031385A1公开(公告)日: 2014-01-30
- 发明人: Stephen D. Barrett , James B. Kramer , Mark L. Boys , Huifen Chen
- 申请人: Stephen D. Barrett , James B. Kramer , Mark L. Boys , Huifen Chen
- 申请人地址: US AZ Scottsdale
- 专利权人: Medicis Phamaceutical Corporation
- 当前专利权人: Medicis Phamaceutical Corporation
- 当前专利权人地址: US AZ Scottsdale
- 主分类号: C07D495/04
- IPC分类号: C07D495/04
摘要:
The present invention provides for compounds of Formula I, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, and R7 have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as therapeutic agents in the treatment of TGFβ-mediated conditions, including cancer and fibrotic disorders. Also provided are pharmaceutical compositions comprising one or more compounds of Formula I.
公开/授权文献
- US09090625B2 Therapeutic pyrazolyl thienopyridines 公开/授权日:2015-07-28
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